Steroid induced cataract treatment

my dad(diabetic) had 140 fasting on the morning of diabetologist told the nurse on phone to give 4 units of he was given…and in an hour,his level came down to surgery was the night after surgery..his ocular pressure had increased,he had mannitol to reduce pressure was gvn only next day…when v reported agin to later tht day v came to knw tht diabetologist was denying tht he said the nurse to gv insulin to my mean he was like i first said the nurse to give bt then later dont know y he behaved tht day,isnt 140 more for fasting,n gvn insulin must have only benefitted him na??
Now 3 wks later,when he is facing probs with vision, n also floaters,doc(opthlmologist) has told he has gt retianl swelling,he was gvn tricot inj. n he is on acular eye drops now for gv info.

I had Lasik surgery the summer of 2009 at age 45. I was considered a good candidate for the surgery. I had very good vision (20/15) for almost 2 years, but then started noticing changes. My regular eye doctor thought that I was simply suffering from dry eye. After about 8 months of treatment, the doctor could see cataracts forming. I just had cataract surgery on my left eye Feb 26, 2014 at age 50, only 2-1/2 years after noticing the first vision degradation. The cataract was rated 3+. This cataract caused blurring and multiple images, rather than cloudiness or discoloration. I also have a cataract forming in my right eye, though it isn't progressing as aggressively as the left eye did. I do not have any health issues such as diabetes, I never took steroids except for the eye drops after Lasik surgery, and I have never had any type of eye injury which would cause early cataracts. I believe that the Lasik surgery or follow-up eye drops caused me to develop early, aggressive cataracts.

Corticosteroids have been used as drug treatment for some time. Lewis Sarett of Merck & Co. was the first to synthesize cortisone, using a complicated 36-step process that started with deoxycholic acid, which was extracted from ox bile . [43] The low efficiency of converting deoxycholic acid into cortisone led to a cost of US $200 per gram. Russell Marker , at Syntex , discovered a much cheaper and more convenient starting material, diosgenin from wild Mexican yams . His conversion of diosgenin into progesterone by a four-step process now known as Marker degradation was an important step in mass production of all steroidal hormones, including cortisone and chemicals used in hormonal contraception . [44] In 1952, . Peterson and . Murray of Upjohn developed a process that used Rhizopus mold to oxidize progesterone into a compound that was readily converted to cortisone. [45] The ability to cheaply synthesize large quantities of cortisone from the diosgenin in yams resulted in a rapid drop in price to US $6 per gram, falling to $ per gram by 1980. Percy Julian's research also aided progress in the field. [46] The exact nature of cortisone's anti-inflammatory action remained a mystery for years after, however, until the leukocyte adhesion cascade and the role of phospholipase A2 in the production of prostaglandins and leukotrienes was fully understood in the early 1980s.

1. Discontinue steroids—In the acute form of IOP elevation from steroids, discontinuing steroids can cause the IOP to normalize in days. In the chronic form, elevation of IOP can last one to four weeks. 26 In a small subset of patients, the IOP may remain chronically elevated despite discontinuation of steroids. In one series, % of eyes converted to glaucoma. Interestingly, all of these patients had a family history of The duration of steroid treatment seems to play a role as well. In one series, the IOP remained elevated in patients where the steroid was used for more than four years. 28 2. Removal of depot steroids—One can cause a decrease in IOP by excising depot ,29,30 For intravitreal steroids, vitrectomy can also be used to reduce 3. Glaucoma treatment—Treatment of steroid glaucoma includes the use of topical glaucoma medications, laser trabeculoplasty, filtering surgery, glaucoma drainage implant surgery, or one of the other means of treatment of primary open angle glaucoma.

Steroid induced cataract treatment

steroid induced cataract treatment

1. Discontinue steroids—In the acute form of IOP elevation from steroids, discontinuing steroids can cause the IOP to normalize in days. In the chronic form, elevation of IOP can last one to four weeks. 26 In a small subset of patients, the IOP may remain chronically elevated despite discontinuation of steroids. In one series, % of eyes converted to glaucoma. Interestingly, all of these patients had a family history of The duration of steroid treatment seems to play a role as well. In one series, the IOP remained elevated in patients where the steroid was used for more than four years. 28 2. Removal of depot steroids—One can cause a decrease in IOP by excising depot ,29,30 For intravitreal steroids, vitrectomy can also be used to reduce 3. Glaucoma treatment—Treatment of steroid glaucoma includes the use of topical glaucoma medications, laser trabeculoplasty, filtering surgery, glaucoma drainage implant surgery, or one of the other means of treatment of primary open angle glaucoma.

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